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Abstract            Volume:14  Issue-9  Year-2026         Original Research Articles


Online ISSN : 2347 - 3215
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcret@gmail.com

Effect of 75% Irvingia gabonensis Flour on Certain Biochemical Parameters in Rats Rendered Obese by Crude Palm Oil
Oulai Tokpa Louya1, N’Guessan Yao Firmin1, Kouamé Djè Kouamé Wenceslas1,2*, Kouadio Kyssy Samira1 and Doumbia Idrissa1
1Polytechnic University of Man, BO box 20 Man, Côte d’Ivoire, Training and Research Unit-Engineering, Agronomic, Forestry and Environmental (UFR-IAFE) 2Nangui Abrogoua University, Department of Natural Sciences, Laboratory of Physiology, Pharmacology and Pharmacopoeia, 02 BO box 801 Abidjan 02, Côte d’Ivoire
*Corresponding author
Abstract:

Obesity is recognized as one of the most alarming public health challenges of the 21st century, characterized by an abnormal or excessive accumulation of body fat that severely impairs health. This study aims to evaluate the effect of supplementation with 75% Irvingia gabonensis flour on obesity induced by a diet enriched with 15% red palm oil in Wistar rats. Fifteen (15) rats were randomly assigned to three homogeneous experimental groups of five animals each. Two diets were formulated for this experiment: a standard diet used to feed the control group, and an obesity-inducing diet created by supplementing the standard diet with 15% crude palm oil (fed to a second group of rats). Finally, a third group—the treatment group—received a diet consisting of 25% of the obesity-inducing diet and 75% Irvingia gabonensis flour. Incorporating 75% Irvingia gabonensis flour into the diet reduced blood glucose levels by 9.2% and LDL-c levels by 85%, and normalized total cholesterol levels compared to the obesity-induced group. This incorporation also reduced the atherogenic coefficient (AC) by 0.184 and the classical ratio by 89.5%, as well as the atherogenic index of plasma (AIP). Thus, Irvingia gabonensis could represent an interesting natural alternative for the prevention and management of palm oil-induced obesity and associated metabolic disorders.

Keywords: Irvingia gabonensis, obesogenic diet, biochemical, rat, atherogenicity, cholesterol
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Int.J.Curr.Res.Aca.Rev. 14(9): 103-108
doi: https://doi.org/10.20546/ijcrar.2026.1409.011
Copyright: This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike license.


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